Yasushi Fujio Selected Research

Interleukin-6 (Interleukin 6)

4/2024	JAK inhibition during the early phase of SARS-CoV-2 infection worsens kidney injury by suppressing endogenous antiviral activity in mice.
1/2017	Adult murine cardiomyocytes exhibit regenerative activity with cell cycle reentry through STAT3 in the healing process of myocarditis.
9/2012	Therapeutic administration of IL-11 exhibits the postconditioning effects against ischemia-reperfusion injury via STAT3 in the heart.
9/2011	IL-6-mediated Th17 differentiation through RORγt is essential for the initiation of experimental autoimmune myocarditis.
2/2010	Therapeutic activation of signal transducer and activator of transcription 3 by interleukin-11 ameliorates cardiac fibrosis after myocardial infarction.
9/2004	Circulating interleukin-6 family cytokines and their receptors in patients with congestive heart failure.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Yasushi Fujio Research Topics

Disease

12	Heart Failure 01/2024 - 09/2004
9	Fibrosis (Cirrhosis) 10/2022 - 02/2010
9	Inflammation (Inflammations) 01/2020 - 08/2004
9	Ischemia 01/2017 - 04/2004
8	Neoplasms (Cancer) 01/2021 - 03/2002
7	Cardiomegaly (Heart Hypertrophy) 01/2019 - 07/2002
6	Reperfusion Injury 12/2023 - 02/2005
6	Hypertrophy 01/2021 - 07/2002
5	Myocardial Infarction 12/2023 - 02/2010
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 03/2008
4	Infarction (Infarctions) 01/2019 - 02/2010
4	Atherosclerosis 01/2012 - 09/2003
4	Cardiomyopathies (Cardiomyopathy) 07/2008 - 07/2002
4	Diabetic Retinopathy (Retinopathy, Diabetic) 03/2008 - 02/2003
3	Infections 04/2024 - 01/2022
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2020 - 09/2013
2	COVID-19 04/2024 - 01/2022
2	Sepsis (Septicemia) 01/2023 - 01/2023
2	Chronic Renal Insufficiency 01/2022 - 01/2021
2	Body Weight (Weight, Body) 01/2022 - 08/2010
2	Hypoxia (Hypoxemia) 01/2022 - 07/2007
2	ST Elevation Myocardial Infarction 01/2018 - 09/2016
2	Myocarditis (Carditis) 01/2016 - 09/2011
2	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 08/2010 - 09/2004
2	Pulmonary Arterial Hypertension 06/2009 - 03/2007
2	Cardiotoxicity 01/2009 - 07/2008
2	Atrophy 05/2008 - 03/2006
2	Muscular Atrophy (Muscle Atrophy) 03/2006 - 01/2006
2	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 07/2004 - 06/2004
1	Cytokine Release Syndrome 04/2024
1	Brain Death (Brain Dead) 12/2023
1	Communicable Diseases (Infectious Diseases) 01/2023
1	Pneumonia (Pneumonitis) 01/2023
1	Viral Pneumonia 01/2023
1	Vascular Calcification 10/2022
1	Type 2 Diabetes Mellitus (MODY) 04/2022
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022
1	Albuminuria 01/2022
1	Ureteral Obstruction 01/2021

Drug/Important Bio-Agent (IBA)

10	CytokinesIBA 01/2023 - 08/2003
7	Interleukin-11 (Interleukin 11)IBA 12/2023 - 05/2007
7	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 09/2003
7	Taurine FDA Link 08/2010 - 04/2004
6	Interleukin-6 (Interleukin 6)IBA 04/2024 - 09/2004
6	Proteins (Proteins, Gene)FDA Link 01/2023 - 03/2011
4	Transcription Factors (Transcription Factor)IBA 10/2022 - 01/2021
4	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2017 - 07/2004
4	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2009 - 03/2002
3	CreatinineIBA 04/2024 - 02/2003
3	InterleukinsIBA 01/2023 - 09/2011
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 02/2016
3	ErbB Receptors (EGF Receptor)IBA 01/2020 - 07/2007
3	LigandsIBA 01/2019 - 08/2004
3	Phosphotransferases (Kinase)IBA 01/2018 - 05/2008
3	Endothelin-1 (Endothelin 1)IBA 06/2009 - 03/2007
3	taurine transporterIBA 05/2008 - 01/2006
2	Carvedilol (Coreg)FDA LinkGeneric 01/2024 - 04/2013
2	Blood Glucose (Blood Sugar)IBA 01/2022 - 03/2008
2	Tyrosine Kinase InhibitorsIBA 01/2021 - 12/2018
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2020 - 12/2018
2	Adrenergic Agents (Adrenergic Drugs)IBA 01/2019 - 02/2008
2	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2019 - 10/2005
2	Calmodulin (Calcium-Dependent Activator Protein)IBA 01/2018 - 04/2013
2	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2018 - 03/2017
2	CalciumIBA 01/2017 - 04/2013
2	OsteopontinIBA 04/2013 - 10/2011
2	Glycoproteins (Glycoprotein)IBA 01/2011 - 02/2010
2	Bosentan (Tracleer)FDA Link 06/2009 - 03/2007
2	Endothelins (Endothelin)IBA 06/2009 - 07/2002
2	Amino Acids FDA Link 05/2008 - 10/2004
2	Messenger RNA (mRNA)IBA 07/2007 - 10/2005
2	Dexamethasone (Maxidex)FDA LinkGeneric 03/2006 - 01/2006
2	Platelet Activating FactorIBA 07/2005 - 08/2004
2	Caspase 9IBA 10/2004 - 04/2004
2	Cytochromes c (Cytochrome c)IBA 10/2004 - 04/2004
2	Anaplastic Lymphoma KinaseIBA 07/2004 - 06/2004
1	InterferonsIBA 04/2024
1	Antiviral Agents (Antivirals)IBA 04/2024
1	Hematoxylin (Haematoxylon)IBA 04/2024
1	Janus Kinase InhibitorsIBA 04/2024
1	Eosine Yellowish-(YS) (Eosin)IBA 04/2024
1	baricitinibIBA 04/2024
1	AlbuminsIBA 04/2024
1	Lipocalin-2IBA 04/2024
1	dicarboxydine (DCD)IBA 12/2023
1	Poly I-CIBA 01/2023
1	salicylhydroxamic acid (SHAM)IBA 01/2023
1	Plasminogen Activator Inhibitor 1IBA 01/2023
1	CollagenIBA 10/2022
1	ipragliflozinIBA 04/2022
1	Tumor Suppressor Protein p53IBA 01/2022
1	Disinfectants (Biocides)IBA 01/2022
1	triciribineIBA 01/2021
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2021

Therapy/Procedure

11	Therapeutics 01/2021 - 12/2010
2	Renal Dialysis (Hemodialysis) 01/2019 - 03/2008
2	Drug Therapy (Chemotherapy) 12/2018 - 05/2013
2	Precision Medicine 12/2010 - 11/2006
1	Heart Transplantation (Grafting, Heart) 12/2023
1	Warm Ischemia 12/2023